Differential Bio

Differential Bio is a Munich-based company developing the Virtual Scale-up Platform, software and laboratory infrastructure for bioprocess optimization. The platform combines scale-down experiments with AI-based modelling to simulate and optimise bioprocesses virtually, reducing the need for costly physical experiments and predicting optimal conditions across scale-up stages. Reported client results include a fourfold increase in biomass yield and a 16% reduction in production costs.

The work draws on several technical fields: artificial intelligence and machine learning, bioprocess modelling and simulation, robotic lab automation, high-throughput screening, microbiology, scale-down experiments, and data generation and standardisation. The underlying aim is to make microbial growth predictable, scalable and cost-effective, integrating microbiology, robotic laboratory automation and AI in a single workflow.

The company's technology is applied across probiotics, food, cosmetics, chemicals, materials and biomanufacturing. Differential Bio has raised €2 million in pre-seed funding and states a long-term ambition to become "The Organism Modeling Company", with the broader goal of making biomanufacturing a smarter, faster and more scalable industry.