ColoWrap, Inc.

ColoWrap, Inc. is a medical device company based in Durham, North Carolina, that develops external compression technology for endoscopic procedures, with a focus on colonoscopy. Its principal product, the ColoWrap Anti-Looping Colonoscopy Compression Device, is a non-invasive, proprietary neoprene-based and latex-free device that applies targeted compression to the abdomen during procedures to mitigate colonoscope looping. Colonoscope looping occurs in up to 90% of colonoscopies and typically requires endoscopists or assistants to apply manual abdominal pressure or reposition the patient.

Reported clinical results indicate that the device reduces the need for manual abdominal pressure by up to 73.6%, patient repositioning by 59.5%, and mean cecal intubation time by up to 23%. More than 100,000 colonoscopies have been performed using the device, with no adverse events reported. The company states a mission focused on improving colonoscopy outcomes and creating a zero-harm endoscopy environment for patients, staff and providers, and it places emphasis on clinical evidence and clinical studies.

ColoWrap is an early-stage medical technology company whose technical work spans medical devices, external compression technology, endoscopy and gastroenterology devices, anti-looping device design, and materials science, including neoprene-based, latex-free materials. It holds more than 15 issued patents and has received a Phase I SBIR grant from the National Science Foundation to support research and development of novel anti-looping devices. Its design philosophy favours non-invasive, "elegantly simple" solutions.